However, we are already supplying and supporting customers who are working Catch up on previous discussions related to COVID-19 research in these podcasts and videos: Let us know what you are working on, so we can mitigate the spread of COVID-19. Authors from the MPI for evolutionary Anthropology in Leipzig present a cheap and fast approach to detect SARS-CoV-2 in single or pooled gargle lavages (‘mouthwashes’), using NEBs Luna Universal RT-qPCR Mastermix. Bernhard Schermer et al., MedRxiv 2020 Jun 22. (T.G. The SARS-CoV-2 Rapid colorimetric LAMP Assay Kit utilizes loop-mediated isothermal amplification for use in the analysis of SARS-CoV-2, the novel coronavirus that causes COVID-19. The spike protein is additionally extensively glycosylated (up to 22 N-glycosylation sites). Fill out our Technical Support Form, Proteolytic cleavage between the S1 and S2 unit of the spike protein of SARS-CoV-2 is an important part of the process to allow viral entry into the host cell after binding to the surface receptor. WarmStart colorimetric LAMP 2X Master Mix is an optimized formulation of Bst 2.0 WarmStart DNA Polymerase and WarmStart RTx in a special low-buffer reaction solution.The mix contains a visible pH indicator for rapid and easy detection of Loop-Mediated Isothermal Amplification (LAMP) and RT-LAMP reactions. Learn about our tools that are helping researchers develop diagnostics and vaccines for the SARS-CoV-2 virus.. Time for Change. The New England Biolabs podcast series, Lessons from Lab and Life, is dedicated to sharing helpful life lessons from successful scientists. Are you doing COVID-19 related research? Our technical support and customer service is also there for you as usual. An exhibition from work completed in the course Painting as Object, at Montserrat College of Art during the fall semester of 2020. Active Pharmaceutical Ingredients (APIs), nor does NEB manufacture its products in compliance with all of the Current Good Manufacturing Practice regulations. Sensitivity of LAMP on extracted RNA and unpurified swab samples are compared. Read More > View All Posts. viral RNA. The following reagents are being recommended in a number of third party COVID-19 sequencing protocols, including “PCR tiling of COVID-19 virus” in Oxford Nanopore Technologies’ Nanopore Community, and the ARTIC protocol. For nearly four decades, NEB has been shaping the landscape of bioscience research by discovering, developing and supporting superior research reagents. Automated RT-LAMP with NEB’s Mastermix includes sample-specific barcodes, reactions are massively pooled and amplified barcodes (i.e. Dec 14, 2020 (The Expresswire) -- "Final Report will add the analysis of the impact of COVID-19 on this industry." 23 – Colorimetric LAMP in point-of-care diagnostics, Successfully used on saliva and buccal swabs as well as simulated nasopharyngeal samples, New streamlined protocol enables extraction from saliva in under an hour, Enables sensitive  downstream detection using RT-qPCR, RT-LAMP and other methods, Successfully used for viral RNA extraction from saliva, buccal swabs, and simulated nasopharyngeal swabs, with the addition of DNA/RNA Protection Reagent (, Extremely fast – extraction complete in under 10 minutes, Enables sensitive downstream detection using RT-qPCR, RT-LAMP and other methods, colorimetric LAMP enables simple, visual detection (pink-to-yellow) of amplification of SARS-CoV-2 nucleic acid, Reduce risk of carryover contamination, with UDG and dUTP included in the master mix, Assay targets N and E regions of the SARS-CoV-2 genome, for optimized sensitivity and specificity, Easily detect amplification with a simple pink-to-yellow color change, Set up reactions at room temperature, as WarmStart feature inhibits activity at 25°C, Real-time fluorescence detection supports high-throughput testing workflows, WarmStart technology enables room temperature setup, Luna Probe One-Step RT-qPCR 4X Mix with UDG (, Luna Universal Probe One-Step RT-qPCR Kit, NEBNext Ultra II RNA Library Prep Kit for Illumina, NEBNext Ultra II Directional RNA Library Prep Kit for Illumina (, NEBNext Ultra II DNA Library Prep Kit for Illumina (, NEBNext Ultra II RNA First Strand Synthesis Module (, NEBNext Ultra II Non-Directional RNA Second Strand Synthesis Module (, NEBNext rRNA Depletion Kit v2 (Human/Mouse/Rat) (, Major processing enzyme of the secretory pathway and is localized in the trans-golgi network, Substrates of furin include blood clotting factors, serum proteins, growth factor receptors, such as the insulin-like growth factor receptor, and the spike protein of SARS-CoV-2, Reaction components compatible with HPLC and mass spec analysis, Analyze complex proteomes with minimal autolysis, Compatible for simultaneous co-digestion with, Suitable for both in-gel and solution digests. 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